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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27468c4a4b12f81cc8db00b2625444bbbb6b2508e89db9cd2a39f78cc3aec7f4' 
  AND token = '8/xeNoMhV9eZe+qQfEAu8yeFNstu1qimOPQTYzEkgMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}