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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '843ea83a668de0810acf26d33498b01d7d2734e71e9f4549e18b07479d79c493' 
  AND token = 'CBRLJ0l+c7tkcDsM8aloQjzGPqa/31ykqG8ZqEEU1z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}