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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e62d4f0a31cce08c4f7c28a5c89f03ad9edd104729153d4e8d511307ee39c3' 
  AND token = 'UU6AKzBhEUQDHPRG0XcgCB0103RJGov2DRKFvWNPLmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}