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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80c512c97d33aa20f1cb5c90354ad23126641cafaefa7e48abd58341ffb4839' 
  AND token = '48v1GFBlOtO+QB2BrQbwd1iPe0gPZZtQ4M8Eozsi+Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}