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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4a9a8548c5a9d1feaa29928067adf6ad32afc331139f8084d694835629c53e' 
  AND token = '6aRtWD8RyS78Vc+6iFOZBklD2Z8G1LXUH542lJE5PS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}