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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db65aea45572eda8dcdd7ea47b3fdce3db80d83d8c2ed03fab889b798bbaa0d' 
  AND token = '/jqxFWaVLpSlOKg7o/bQ/xN3rLOkyt0GK8AqZBlFlNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}