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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e9e00366b14c472ab0a205d81b8f29e9a91ef7b6af30f1f241edfe1ed8cdf5' 
  AND token = 'P2RSG/uEhjK53yAchi/aFRPFmzGjne1R71ZZD2NMr4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}