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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6756bf12c107df6327b783d56aae6017a6fddc766f508f2cb1e5a15c9e646cf5' 
  AND token = 'WemtVZFgedpFA4UCzzHq9KoInRVnqoTrtbsV/4W1pcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}