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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227d27c08a0a76244dafa4163db247a55e947f0f28b2626505285a026a10400e' 
  AND token = 'IG+nAuTn9CUHnGHMLrGB+t9sC+W0j/Oe6XIg2tO2fRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}