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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76a4e1bffb809fa7399272dd225a24dabbd4b76f5f70363a36f1c5644a7f7d6f' 
  AND token = 'IBKVse/O3E3bRZq2znHDzXlM/ve0dsNf5klN34bVbYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}