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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b767600d94e173f2cb2235fecec7eda318ba7bc36615a554e55abc5373417b' 
  AND token = 'z6I9Fq0SFWSU/xMvdIH//G9mzcRgoN3z8TnF/gWQ+Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}