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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7428e79254c386625a5da1aadeaaf4c224bcc3983705a364d271fbf017e60a5b' 
  AND token = '1kfOMbIfQcYnOTbmitmlpXvNX1wp+/CW6uxoKC7OmbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}