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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66042f64d5c3b3f6eee932404d9690f85e1fa8ae349a6e934c973d9a932be2ab' 
  AND token = 'smyYP/BeqDXlGhZwOk9VHs5EH2gPqhVYS9a63Cz6IIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}