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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d67ef37c0f174a7a6cae2add20897aaf9e5ecc1c0b6c33cabacb5af452493f0' 
  AND token = 'Y+tfeSnxUYJN7MTn0dgQ4t45iXNT55U8/KaDzaQ8PO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}