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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b10318fb5682267e81c6ffd4935d7818f689fc0b8de904d87c61de89c2186f7f' 
  AND token = 'I+MIKLhUDpSdAXUAO8Js0PN4qloGQfR7vaV0NcxJVdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}