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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ed7186dbdd72c2d9c5409db1e25845a3088b11ef92df067da56a04e926eeb3' 
  AND token = 'ma7o6EoMMJW1UrGrRldPwGW5ZjYRIaG0lj3Hk1D2de0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}