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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35b26a035f23afa1f96067f6f9ddc19f6eef5c5da68e2ffb4d65633e27fa481' 
  AND token = 'dE3vxnHuk/DcUsKbOmGDc7szHuFMJXP6MTjPBNgvk4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}