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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eccc21fe79bdc6830307f97eb3a56cb4ea942cced112b171484d7766e9d6967a' 
  AND token = 'JsUgdMJJ1w9ZQFNRys8gQW9fyrwx4FqS80pkYppGK+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}