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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed94614767f21da0f49ac6318d02971ae3913a8c7c9ba105067755fac576616f' 
  AND token = 'AmywWmHFsMXQvdNap84/OB2qWYL/PN0mePim5GVo7Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}