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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00282d0c43485f067563a23c01abd40830df1b5a8d125fbc3166be6cf0b908c5' 
  AND token = 'vGsaK9bjJL+QbMRiOwUuUkN3g4OguVOIvGraHe4OSJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}