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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a2025f76bb3f0495f91dab51b6bfac16016cebcf409d313d3a3fd040a882862' 
  AND token = 'BUbzrF1uB/RBPhPC4Q/JFt6QJgCSrfa5xEDdczvXUmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}