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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '877eb9868256652da19c6aa68fad1af327121b8c6ba4622550c3066af7397268' 
  AND token = 'oY/Vv/aVsGnAnDHRB0sfm38BWv2xExKkScR5v3amBSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}