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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6464da88901ff7f26311a639cba62c2a4440523463a0bc4ac71f03dbca992684' 
  AND token = '2Mlbued4vN3LWILmBy4q8F4XEM746EgEGd9kCcm+adM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}