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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20637ee85fde0e62a79dbb8ea926d94b067e043d4085a6d33f4a27fc89037249' 
  AND token = 'hUY6YwozPsoy6j0o07jjeHxsX0g6r7Nongl0vSWEf9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}