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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e427b9842cdd7a4542c226fab94a64f8f3976244ff1dad09fe10bf9e210ed20' 
  AND token = 'UvPIpCokRHSTIK1zdvsbZyyc6l+TqiKUMRsb2qOQi9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}