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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224ebe3577a7a64ad1e6743a68366de4bd7f62c1e7a032e70b559640338e87ff' 
  AND token = 'S+h2HEJCuCwNf0idX1Xo8zJT8oL3vSe0j/t9aKoF4Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}