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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acc912c584595d112cb91a0bf23ba978811884c929997298ce8b123cbf2486f2' 
  AND token = 'wHOSEU7UdUgHa6/KXSl1H1+ik9UsWp/rHyjkZ6i8SmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}