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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e298ce218da5f23df4d25c815a91bb5571e1e31b0c5fd61b50b834bb1dd87fee' 
  AND token = 'R0gPwtwiBAT6Rl4h/EV3emsCtlprWb0zYOBEt2zAjPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}