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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d1f18f6e7c45e90e089a40ad6eadab75606bc865ff377043ff074990a73d1f' 
  AND token = 'dkdmQNUajvx3/h05Ghg4hTB6ELhPn8FsFuIRMnnj/ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}