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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca064272ebe7acaeb0023003d6b57e4a607384cf1b8a14bbac70844d88f7817' 
  AND token = 'DA/zQa22qTCgSvsUNtErb4YIWs+Bd5MV4TUEhtIqp7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}