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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25912e298cddbe81dd5ce727d0d8084d7c0cb0b43d7ad697ff6ad053a24053e0' 
  AND token = 'iU+w5WkxdLMTywTxw8abOGlGl2Qe0JPKgJ8oJ9wznLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}