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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0ff7749d7df64586e206dff65e1d623434f5a731948e381531979b24eca1177' 
  AND token = '5ZjnAcTHm50UY08d0klfqqUeoguEBgw50cD7U1xqsCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}