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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65bc20b7e8bc048d3782ff20a8726e4bd52e80627e87b314966019df36ee68b2' 
  AND token = '1m8phtOkFBvjs85oy0CYa2HMrlbL0+8IQ7HFqBVtNUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}