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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727d998b22794d7bdf76e96e7a47bd654e79a138d5efa701cf4f9be552d5f2d1' 
  AND token = '/O2zymgHb/K48koLYT/FBWggkfRQtKP1/cvxZ/eQ99s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}