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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf40730b97d4c00dd00b7caa8c1afd6174a050166d7b52bf42f2cb9c7f345c20' 
  AND token = 'LqE75W21gYuMxvW0etAwI+I8HPXpnPb4RmIuUtIhiog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}