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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d08d9563a02f8ed4202a00c7167f55cdab0f88b4b2f5aaa62043b250e784000' 
  AND token = 'W6tpKU9XxpgaDFch4rVd1odApwcwBA69HcoWY7kw1AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}