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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e21a8ec48e817838f92fa0964f0598ca52f2545762eb71e827ad6534a8d77a1' 
  AND token = 'rCIXoHt3DzyKxIO3xS28WGEGTd5BEuZlvjZ6TaL5rM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}