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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066bf078006526169ad6994922ee9ed215f3a99b6123a6f67af8838029fc639b' 
  AND token = '8CPyx70gfahi0S8jzTyvvanOMzOIq9pcmDp4D7AoDms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}