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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe22940ac77b47ad7ea9617b7e9037fdfb73c8d8fe5a17e99b218f5988e59bb' 
  AND token = 'XPhSVb+9U3RrfhGYvs0hgdeK0KrlefK57OTwxNB01iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}