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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9bee04fdabde5c63ab19fdc5ea01361c8383171c0772f4261da7c77721b88f' 
  AND token = 'YW6rmP6cv9aOfpv3D+X1huPgMT2wH3xYuRGAX3LKkYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}