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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '326494051930ba174e76b574e17333cdca4d671461e00c6ff3ba863b6e7f036d' 
  AND token = 'PqY0ez65EKwilK/Sm2IfjRfNgVikG9kYGMum78mX6sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}