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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e512f9f1ce9a748c54fe1f03c90c9f1ee7d6c36b4d64057dbcb98453fcb22aa8' 
  AND token = 'VOmXdqqIU71sm64IriZZz6o5XHr6MAiQOExRgyrhWu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}