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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b195391d6e32c171e703c5c1c3d6b97bd8ddbee9dc8270dcaad46124b676b5b2' 
  AND token = 'tdU/Qq6ofbKT0oywG29KeaWjzrSAFGN/jUcE5KvGFP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}