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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e262bcb5d5c74caa282d190aea33e025e1d5cfa9f6204072a3632ae7f441d5d' 
  AND token = 'BBgVSPVYGEg6+cBS4X2X4Qo4GdZ1yoS3RuU0yEhToU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}