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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89a2b1fe37b8dd646fad0b9a0076112ed886683dc0f5d64ac392670e94f487cb' 
  AND token = 'HoLl4yb0MQZbATlhEvETRwmfRVcMvQROrNrT69e4xIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}