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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f58bd3060e756f911ab564b867dc3b4188b43e3cd4961d8632e7b9f8c11878' 
  AND token = 'Ko4wlSntjSM3/n1u3M4LDQRRW8I7td2L2I+w3BucK6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}