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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5523fcdcad5aef8114267d5f687f30bfda1aff1fdc9ce941c274fa7d21804d6b' 
  AND token = 'saZ9CsudjGRQDV7FgR6nA7CHSxUkH6c5fIoGWBVyX7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}