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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c3dd3fc5a71a17f14fd2e03ec9cc517c1a7a4d37345910144d3ed3c6a74109' 
  AND token = 'BxBL8u8HPdD4wSFlUvDLfZlSMgas9TcpfQfP08Pw4D0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}