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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff399fa99d76edab300f8d8f56a386dbbd4bc76f2a5e9a3b2a9b196c7a9f51cb' 
  AND token = 'j4nKodnPv5DgeGuADr/nf/uicE1DNN9Rjo+iG26Tx40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}