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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08301e4ff880648c13d8cefb3f4aabc70dacb2ccbb1296ca7ff3a20d5b6c7839' 
  AND token = 'Z2bIAm9OZ9rrjyOAzpcRVff43DqDX7PQngIiXNY16mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}